Thoroughly to be certain the tympanic membrane is not ruptured in order to avoid Treatments, therapy with a rapidly acting corticosteroid should be considered inīefore instilling any medication into the ear, examine the external ear canal Patients presently receiving or recently withdrawn from corticosteroid Result in endogenous steroid production inhibition following drug withdrawal. Use of corticosteroids, depending on dose, duration, and specific steroid, may Prolonged use or overdosage may produce adverse Sodium retention, potassium loss, fluid retention, weight gain, polydipsia,Īnd/or polyuria. Patients should beĬlosely observed for the usual signs of adrenocorticoid overdosage which include Oral ingestion of some topical corticosteroid preparations. Adverse systemic reactions have been observed following the Treatment, discontinue use of OTOMAX immediately and flush the ear canalĪdministration of recommended doses of OTOMAX beyond 7 days may result inĪvoid ingestion. If hearing or vestibular dysfunction is noted during the course of Warnings: The use of OTOMAX has been associated with deafness or partial hearing loss inĪ small number of sensitive dogs (eg, geriatric). Shake well before use when using the 215 gram bottle.įederal law restricts this drug to use by or on the order of Oil-based system containing a plasticized hydrocarbon gel. Veterinary equivalent to 3 mg gentamicin base betamethasone valerate, USPĮquivalent to 1 mg betamethasone and 10 mg clotrimazole, USP in a mineral Do not use in dogsĪctive Ingredients: Each gram of OTOMAX contains gentamicin sulfate Use of drugs known to induce ototoxicity should be avoided. Treatment should be discontinued and appropriate therapy instituted. TherapyĬontraindications: If hypersensitivity to any of the components occurs, Instill 8 drops (4 drops from the 215 gīottle) twice daily into the ear canal of dogs weighing 30 lbs. After verifying that the eardrum is intact, instill 4ĭrops (2 drops from the 215 g bottle) of OTOMAX twice daily into the ear canal Excessive hair should be clippedįrom the treatment area. Remove foreign material, debris, crusted exudates,Įtc., with suitable non-irritating solutions. Resistance to clotrimazole is very rareĪmong the fungi that cause superficial mycoses.ĭosage and Administration: The external ear should be thoroughly cleanedĪnd dried before treatment. The primary action of clotrimazole is against dividingĬlotrimazole exhibits fungistatic and fungicidal activityĪgainst isolates of Trichophyton rubrum, Trichophyton mentagrophytes,Įpidermophyton floccosum, Microsporum canis, Candida spp., and Malassezia The treatment of dermal infections caused by various species of pathogenicĭermatophytes and yeasts. Clotrimazole: Clotrimazole is a broad-spectrum antifungal agent that is used for.
Systemically administered corticosteroids. Once absorbed through the skin, topicalĬorticosteroids are handled through pharmacokinetic pathways similar to InflammationĬan increase percutaneous absorption.
Topical corticosteroids can be absorbed from normal, intact skin. Management of corticosteroid-responsive otitis externa. To provide anti-inflammatory and anti-pruritic activity in the topical Betamethasone, an analog of prednisolone, has a high degree ofĬorticosteroid activity and a slight degree of mineralocorticosteroid activity.īetamethasone valerate, the 17-valerate ester of betamethasone, has been shown Betamethasone: Betamethasone valerate is a synthetic adrenocorticoid forĭermatologic use.Gentamicin is active against the following organisms commonly isolated fromĬanine ears: Staphylococcus aureus, other Staphylococcus spp., PseudomonasĪeruginosa, Proteus spp., and Escherichia coli. Inhibiting normal protein synthesis in susceptible microorganisms.
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